The Mullingar native played his two solo hits before launching into the new track when performing live on NBC's the Today Show earlier this week.
Just before the 23-year-old sang his hit song 'This Town', he told the audience: "Before I start, I would like to dedicate it to the people who lost their lives in Manchester last week. It was a very sad thing, so I just, it's the least I can do is dedicate this song."
After the show, Niall Horan took to Twitter to say: "Great time on @TODAYshow. Thank you for having me and seriously thank you for coming out in your thousands, I really felt the love out there."
You can watch him perform the new song 'On The Loose' here...